Rats overexpressing the dopamine transporter display behavioral and neurobiological abnormalities with relevance to repetitive disorders
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منابع مشابه
Rats overexpressing the dopamine transporter display behavioral and neurobiological abnormalities with relevance to repetitive disorders
The dopamine transporter (DAT) plays a pivotal role in maintaining optimal dopamine signaling. DAT-overactivity has been linked to various neuropsychiatric disorders yet so far the direct pathological consequences of it has not been fully assessed. We here generated a transgenic rat model that via pronuclear microinjection overexpresses the DAT gene. Our results demonstrate that DAT-overexpress...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep39145